BDBM283845 US10023562, Example 37

SMILES [2H]C([2H])([2H])OC(C)(C)[C@H](F)CNC(=O)c1cnc(Nc2ncc(cc2F)C#N)cc1NC(C)C

InChI Key InChIKey=JTLRIQVZZHIXPT-SLXNOQCVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283845   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM283845(US10023562, Example 37)
Affinity DataIC50:  4nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent